Trophies:

Bronze trophies
Destiny Begins – Select a Power.
Think About It… – Make first power destiny choice.
Choose Wisely – Make second power destiny choice.
The Choice Is Made – Make third power destiny choice.
Splicer – Equip your first X-Gene.
At Least It’s Aerodynamic… – Equip your first suit.
I’ve Got the Power – Fully level up a power.
Four of a Kind – Equip a complete X-Gene set and suit.
Beginner’s Luck – Complete your first Great combo.
This can’t be happening! – Complete your first Insane combo.
How Strong Could It Be? – Trigger X-Mode.
Broken Glass, Everywhere… – Break 30 Combat Text Pop Ups.
Fight Terror with Terror – Defeat 10 enemies with one Ultra power.
Side-tracked – Complete your first challenge mission.
Taking Every Opportunity – Complete 10 unique challenge missions.
Garbage Collection – Destroy your first piece of propaganda.
Profiler – Collect your first dossier.
Purify the Purifiers – Defeat 2000 Purifiers.
Mechageddon – Defeat 20 Purifier Stalker Mechs.
Reinforced – Defeat 20 Prime Enforcers.
U Mad, Bro? – Defeat 30 U-Men in the Secret Lab.
The Goon Squad – Defeat 500 MRD Troops.

Silver trophies
Got My Eye on You – Join Cyclops and the X-Men.
Magneto Is Right – Join Magneto and the Brotherhood.
Fully Evolved – Fully level up all powers.
Completionist – Complete all 15 unique challenge missions.
Cleaned up the City – Destroy 25 pieces of propaganda.
Archivist – Collect 15 dossiers.

Gold trophies
Beta Level Mutant – Finish the game on New Mutant difficulty.
Alpha Level Mutant – Finish the game on X-Man difficulty.
Omega Level Mutant – Finish the game on X-treme difficulty.

Platinum trophy
Homo Superior – Earn all Bronze, Silver, and Gold trophies.